MONCYTE Health diagnostics, developing proprietary technology to optimize treatment and prevention of cardiovascular disease, has closed a EUR 1 million seed round to fund its go-to-market strategy. Its technology is designed to help clinicians select more effective personalized treatments for patients with high cholesterol. The round was led by Finnish venture capital investors Inventure, Almaral, and Athensmed and included funding from University of Helsinki Funds, private European investors, and a grant from Business Finland.
Cardiovascular disease is the primary cause of death worldwide, with high cholesterol being one of most important risk factors of the disease. High blood cholesterol can lead to the formation of atherosclerotic plaques, which are fat deposits in arterial walls that can block the blood flow and lead to heart attack and stroke. Currently, a significant proportion of high-risk patients do not achieve optimal blood cholesterol levels and remain at elevated risk for cardiovascular disease.
MONCYTE Health has a unique proprietary technology to quantify individual differences in cellular lipid uptake and storage which contribute to high blood cholesterol and the effectiveness of common lipid-lowering drugs. The readouts are derived from white blood cells, including monocytes, which play key roles in atherosclerotic plaque formation and inflammation, linking directly to cardiovascular risk. Precisely quantifying these individual differences enables personalized treatment strategies in combination with risk assessment which can help patients more effectively achieve optimal blood cholesterol levels faster, and thereby reduce the risk for cardiovascular disease. The technology also provides insight for pharmaceutical companies about how novel lipid-lowering drugs influence the cellular processes contributing to cardiovascular risk.
“Over 1.5 billion people world-wide are affected by high cholesterol. Our technology focuses on how cholesterol is transported and processed in human cells, and since the most important cholesterol-lowering treatments function at the cellular level, this type of technology is essential to disease understanding and identifying opportunities for developing novel drugs and personalized therapies for high cholesterol”, says Tamara Alagirova, CEO and co-founder at MONCYTE Health. “We are extremely happy to receive this funding, which will support the development of our unique diagnostic technology and can make a real difference in improving health. We believe that personalized approaches for more effective lipid-lowering therapy and better insights into how immune cells accelerate plaque development can prevent heart attack and stroke more effectively.”
“Investing in MONCYTE Health was a compelling choice for us, driven by the exceptional expertise of the team and initial traction of the market. We are excited to embark on this journey together and make an impact,” said Maria Severina, CEO and Founder at Almaral.
MONCYTE Health’s technology is significantly different from other diagnostic tests. Rather than quantify biomarkers which are present in blood, MONCYTE Health quantifies the cellular processes that affect the biomarkers. This unique insight provides the possibility to predict an optimal treatment strategy and to overcome current approaches of trying out different medications over time.
For additional information:
Tamara Alagirova, CEO & co-founder
ta@moncyte.com
www.moncytehealth.com
Dr. Maria Severina, Founder, CEO
maria.severina@almaral.eu
+358405540127
www.almaral.eu
About MONCYTE Health
MONCYTE Health diagnostics is developing pioneering technology that provides quantitative insight into the biological processes that give rise to high blood cholesterol and how they are different in individuals. MONCYTE Health provides new data for clinical use and enables novel readouts for pharmaceutical companies developing lipid-lowering treatments.
In 2024 it raised a seed round of EUR 1 million, from Finnish venture capital investors Inventure, Almaral, and Athensmed including funding from University of Helsinki Funds, private European investor, and a grant from Business Finland. The company is based in Helsinki, Finland.
For more information, visit moncytehealth.com and follow us on LinkedIn.
About Atherosclerosis
Atherosclerosis is characterized by the accumulation of fatty deposits in artery walls. These fat deposits are called plaques. Plaques can grow, destabilize and rupture, resulting in an obstruction of the blood flow through the artery. If this happens in an artery supporting the heart it leads to a heart attack, if the artery supports the brain it results in a stroke. Heart attack and stroke are cardiovascular diseases.
Elevated blood lipids, especially high cholesterol (LDL-cholesterol (low-density lipoprotein cholesterol)), cause the formation of atherosclerotic plaques and long-term exposure can lead to heart attack and stroke. Maintaining low levels of blood lipids is known to prevent the formation of atherosclerotic plaques and effective lipid-lowering therapy can reduce the burden of existing plaques.
Plaque formation is associated with the recruitment of immune cells which play key roles in inflammation. Inflammation can accelerate the formation of atherosclerotic plaques and render plaques more prone to rupture. This might explain why some individuals have a higher risk for heart attack or stroke as compared to others.